Worksheet: Control of Blood Glucose

In this worksheet, we will practice describing the control of blood glucose by insulin and glucagon as an example of negative feedback.


The concentration of glucose in the bloodstream needs to be carefully controlled; otherwise, there can be serious effects on the body. Which of the following is not one of these effects?

  • ALow blood sugar, resulting in fainting
  • BHigh blood sugar, damaging blood vessels
  • CLow blood sugar, resulting in excessive energy
  • DHigh blood sugar, damaging organs


Glucose is a sugar required by the human body for energy. What is the primary source of glucose for humans?

  • ACarbon in carbon dioxide
  • BSugars and minerals in water
  • CProteins in the diet
  • DOxygen in the air
  • ECarbohydrates in the diet


When glucose is not being used, it can be stored in the liver as an insoluble compound. What is the compound it gets stored as?

  • ACellulose
  • BGlucagon
  • CGlycogen
  • DInsulin
  • EStarch


Controlling blood sugar levels is an important part of homeostasis. What is homeostasis?

  • AThe maintenance of a changing external environment
  • BThe maintenance of a constant external environment
  • CThe maintenance of a constant internal environment
  • DThe maintenance of a constant body temperature


What is the main hormone released when blood glucose is too high?

  • AGlycogen
  • BFSH
  • CInsulin
  • DGlucagon
  • EAdrenaline


Which of the following will decrease a person’s blood glucose level?

  • AJogging 5 km
  • BDrinking an isotonic sports drink
  • CSnacking on crisps and sweets
  • DEating a large meal


The diagram shows the major organs involved in digestion in the human body.

Using the diagram, give the letter and the name of the organ that releases the major hormones involved in regulating blood glucose concentration.

  • AA: Liver
  • BC: Small intestine
  • CB: Pancreas
  • DD: Stomach

Using the diagram, give the letter and the name of the organ that stores glucose as glycogen.

  • AC: Small intestine
  • BB: Pancreas
  • CD: Liver
  • DA: Liver


What is the main hormone released when blood glucose is too low?

  • AGlucose
  • BGlycogen
  • CGlucagon
  • DInsulin
  • EEstrogen


For the following statements about blood glucose, state the key scientific terms being described.

What main hormone is released in response to a decrease in blood sugar?

  • AGlucose
  • BGlucagon
  • CGlycogen

What is the name of the polysaccharide storage molecule that sugar is converted to in the liver?

  • AGlycogen
  • BGlucose
  • CGlucagon

What do we call the main sugar that is obtained from carbohydrates to be broken down in cellular respiration?

  • AGlucose
  • BGlucagon
  • CGlycogen


The diagram provided shows a basic outline of the mechanisms of control of blood glucose.

What hormone is represented by A?

  • AInsulin
  • BGlucagon

What hormone is represented by B?

  • AGlucagon
  • BInsulin

What type of feedback mechanism is the control of blood glucose an example of?

  • ARegulatory feedback
  • BCircular feedback
  • CNegative feedback
  • DDynamic feedback
  • EPositive feedback


Which of the following activities will increase a person’s blood glucose level?

  • ASleeping 8 hours
  • BGoing for a long walk
  • CEating a large meal
  • DSprinting 100 meters


What cellular process in the body breaks down glucose to release energy?

  • ASynthesis
  • BPhotosynthesis
  • CMitosis
  • DRespiration
  • EBreathing

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