Question Video: Defining the Term “Noncoding DNA” | Nagwa Question Video: Defining the Term “Noncoding DNA” | Nagwa

Question Video: Defining the Term “Noncoding DNA” Biology • Third Year of Secondary School

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What is meant by noncoding DNA?

02:15

Video Transcript

What is meant by noncoding DNA? (A) DNA that has no use and it’s only found within prokaryotic organisms. (B) DNA that does not contain instructions for making proteins. (C) DNA that is single-stranded rather than double-stranded. (D) DNA that can’t be extracted from the organism. (E) DNA that is not present within the genome.

Let’s go over what we know about DNA. DNA, or deoxyribonucleic acid, is the molecule that carries the genetic information in all living organisms. A molecule of DNA is most commonly composed of two strands, each of which is a chain of individual units called nucleotides. We can see these different nucleotides here and the corresponding nucleotide sequence of one of these strands as it coils around the opposing strand.

In humans, if we look at the complete sequence of DNA, or our genome, it’s over three billion nucleotides long. We discovered this after sequencing the human genome during the Human Genome Project, which was a worldwide effort by multiple scientists that took over 10 years to complete.

Besides learning about the size of the human genome, we also discovered that our genome contains over 20,000 protein-coding genes, which represents about one percent of our genome. This includes sequences that code for proteins, such as insulin or hemoglobin. The remaining 99 percent of our genome is made up of noncoding DNA. This is a DNA sequence that doesn’t code for proteins. These sequences can include structural RNA, such as ribosomal or rRNA, or regulatory RNA molecules like micro-RNA. However, about half of our DNA is made up of repetitive DNA sequences with no clear function.

Going back to our question, the option that best describes what is meant by noncoding DNA is given by answer choice (B), DNA that does not contain instructions for making proteins.

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