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Question Video: Explaining Why the Pancreas is a Mixed Gland Biology • Third Year of Secondary School

Why is the pancreas referred to as a mixed gland? [A] The pancreas contains endocrine cells that secrete hormones and exocrine cells that secrete enzymes. [B] The pancreas contains exocrine cells that secrete hormones and endocrine cells that secrete enzymes.

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Video Transcript

Why is the pancreas referred to as a mixed gland? The pancreas contains endocrine cells that secrete hormones and exocrine cells that secrete enzymes. Or the pancreas contains exocrine cells that secrete hormones and endocrine cells that secrete enzymes.

Let’s approach this question by first defining some of the key terms that’ve been used. Endocrine glands secrete hormones directly into the bloodstream, and exocrine glands secrete substances via ducts, usually onto body surfaces, such as the skin or the inside of the digestive tract. This diagram represents the human pancreas. The pancreas contains endocrine cells within regions called the islets of Langerhan, which are shown here in pink. These endocrine cells in the islets of Langerhan produce and secrete hormones, such as insulin and glucagon, releasing them into the bloodstream. Once in the blood, these two hormones can travel to their target cells in order to have an effect, which is to increase or decrease blood glucose concentration to maintain it within a normal healthy range.

Most of the pancreas is made up of exocrine tissue, which consists of clusters called acini, which contain pancreatic acinar cells, which we can see here in orange surrounding this green structure, which is the pancreatic duct. The acinar cells within the acini secrete digestive enzymes into this pancreatic duct, which then empties into the small intestine, where these enzymes are responsible for breaking down proteins, lipids, and carbohydrates in the food that we eat. As the pancreas has both endocrine and exocrine functions, it is sometimes referred to as a mixed gland.

Let’s use this information to answer the question. We know now that endocrine cells secrete hormones and that the exocrine cells of the pancreas secrete enzymes. So this option must be the correct answer.

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