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Lesson Worksheet: Proteins Biology

In this worksheet, we will practice describing the synthesis, structures, and functions of proteins.

Q1:

Which of the following best explains the role of hydrogen bonds in protein structure?

  • AHydrogen bonds form within amino acids to join the carboxyl group to the amino group.
  • BHydrogen bonds form between amino acids to hold the protein in its secondary-structure shape (e.g., alpha-helix).
  • CHydrogen bonds form between amino acids to hold them in a polypeptide chain.
  • DHydrogen bonds form between amino acids and water molecules to contribute to the quaternary structure of the protein.

Q2:

Proteins are complex macromolecules formed from polypeptide chains. What monomers join to form polypeptides?

  • AGlycerol
  • BLipids
  • CFatty acids
  • DSimple sugars
  • EAmino acids

Q3:

Which of the following best describes the primary structure of a protein?

  • AThe primary structure of a protein refers to the sequence of amino acids in its polypeptide chain.
  • BThe primary structure of a protein is the complex 3D structure formed when multiple polypeptides interact and combine.
  • CThe primary structure of a protein is the 3D structure that forms due to interactions between the R groups of amino acids.
  • DThe primary structure of a protein is the folded structure (alpha-helix or beta-sheet) formed by additional bonds formed in the polypeptide chain.

Q4:

Which of the following best describes the quaternary structure of a protein?

  • AThe quaternary structure of a protein is the 3D structure that forms due to interactions between the R groups of amino acids.
  • BThe quaternary structure of a protein is the folded structure (alpha-helix or beta-sheet) formed by additional bonds formed in the polypeptide chain.
  • CThe quaternary structure of a protein is the complex 3D structure formed when multiple polypeptides interact and combine.
  • DThe quaternary structure of a protein refers to the sequence of amino acids in its polypeptide chain.

Q5:

Which of the following best describes the secondary structure of a protein?

  • AThe secondary structure of a protein refers to the sequence of amino acids in its polypeptide chain.
  • BThe secondary structure of a protein is the folded structure (alpha-helix or beta-sheet) formed by additional bonds that are formed in the polypeptide chain.
  • CThe secondary structure of a protein is the 3D structure that forms due to interactions between the R groups of amino acids.
  • DThe secondary structure of a protein is the complex 3D structure formed when multiple polypeptides interact and combine.

Q6:

Which of the following best explains the structure of a polypeptide?

  • AA polypeptide is a protein formed by the joining of three amino acids to a glycerol molecule.
  • BA polypeptide is a chain of amino acids joined together by carboxyl bonds between the amino groups of each amino acid.
  • CA polypeptide is a chain of amino acids joined together by peptide bonds between the carboxyl group of one and the amino group of another.
  • DA polypeptide is a chain of proteins joined by peptide bonds between the hydrogens of each protein.

Q7:

Which of the following best describes the tertiary structure of a protein?

  • AThe tertiary structure of a protein is the folded structure (alpha-helix or beta-sheet) formed by additional bonds that are formed in the polypeptide chain.
  • BThe tertiary structure of a protein is the complex 3D structure formed when multiple polypeptides interact and combine.
  • CThe tertiary structure of a protein refers to the sequence of amino acids in its polypeptide chain.
  • DThe tertiary structure of a protein is the 3D structure that forms due to interactions between the R groups of amino acids.

Q8:

The following is a list of bonds found in biological molecules:

  1. Hydrogen
  2. Ionic
  3. Phosphodiester
  4. Disulfide bridges
  5. Glycosidic

What bonds are commonly present in the tertiary structure of proteins?

  • AI only
  • BI, II, and IV
  • CI and IV only
  • DII, III, and IV
  • EI, II, and III

Q9:

Keratin is a long protein found in hair and nails, with many repeats of the sulfur-containing amino acid cysteine. Using the table provided, determine the group of proteins that keratin is most likely to belong to.

ProteinGlobularConjugatedFibrous
PropertiesCompact, roughly spherical, and water-soluble Proteins with a prosthetic groupLong and insoluble with a repetitive primary structure
  • AGlobular
  • BFibrous
  • CConjugated

Q10:

Part of the basic structure of an amino acid is provided. Give the molecular formula of the functional group that is missing.

  • ANH+4
  • BNH2
  • CCH3
  • DCOOH

This lesson includes 24 additional questions and 1 additional question variation for subscribers.

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