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Lesson Worksheet: Specific Immune Response: Antibodies Biology

In this worksheet, we will practice describing the process of clonal expansion and antibody formation in response to an antigen.

Q1:

What type of immune cell is activated by the presence of a processed antigen on the surface of B cells and macrophages?

  • APlasma cell
  • BB memory cell
  • CNeutrophil
  • DT-helper cell
  • ENatural killer cell

Q2:

What type of immune cells secrete antibodies?

  • AMacrophages
  • BMemory cells
  • CT-helper cells
  • DNeutrophils
  • EPlasma cells

Q3:

What cellular process is necessary before antigens can be processed and presented?

  • ADifferentiation
  • BMitosis
  • COpsonization
  • DExocytosis
  • EEndocytosis

Q4:

How are memory cells different from plasma cells?

  • AMemory cells are no longer able to multiply and differentiate.
  • BMemory cells have only one type of antibody receptor on their cell surface whereas plasma cells have many different types of antibody receptors.
  • CMemory cells have a higher rate of protein synthesis.
  • DMemory cells remain in the circulation for a longer time period.
  • EMemory cells are able to respond to a wider range of antigens.

Q5:

HIV infects and destroys T-helper cells. How would an HIV infection affect the body’s antibody response to a new bacterial infection?

  • AThe antibody concentrations would rise higher and faster.
  • BOnly one type of antibody would be produced.
  • CThe same level of antibodies would be produced but it would take longer.
  • DFewer antibodies would be produced by B cells.
  • EThere would be no effect on the antibody response.

Q6:

What triggers the activation of a B cell to start clonal expansion?

  • ABinding to a specific antigen and interleukin release from a T-helper cell
  • BBinding to a specific T-helper cell and interleukin release from a natural killer cell
  • CBinding to a specific macrophage and interleukin release from a T-helper cell
  • DBinding to a specific T-helper cell and interleukin release from a macrophage
  • EBinding to a specific antigen and interleukin release from a macrophage

Q7:

The figure shows a B lymphocyte with antibody (immunoglobulin) receptors on its surface membrane.

Which statement is not true?

  • AEach B cell will have a different type of antibody receptor on its surface.
  • BEach B cell has only one type of antibody receptor that binds to one specific antigen.
  • CThe B cell antigen receptor has a similar structure to a soluble antibody.
  • DThe B cell can bind to extracellular and intracellular antigens.
  • EThe B cell antibody receptor is complementary to an antigen.

Q8:

The figure shows an early stage in the humoral immune response.

What happens next?

  • AThe B cell secretes antibodies.
  • BA T-helper cell binds to the MHC-antigen complex.
  • CA T-helper cell releases interleukin 2.
  • DThe B cell releases interleukin 2.

Q9:

The figure shows a pathogen that has entered the body.

How many types of B cells and antibodies would be formed as a result of the stimulation of the humoral immune system?

  • AFour B cell clones and four different types of antibodies
  • BFour B cell clones and fifteen types of antibodies
  • COne B cell clone and fifteen types of antibodies
  • DOne B cell clone and four types of antibodies

Q10:

The figure shows a type of cell surface protein (in green), called MHC, present on B cells.

What is its function?

  • ATo respond to interleukins from T-helper cells
  • BTo bind with another type of antigen on a pathogen
  • CTo activate phagocytosis in neutrophils
  • DTo present processed antigens for T-helper cells to detect
  • ETo bind to the histamine released from mast cells

This lesson includes 22 additional questions for subscribers.

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