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Lesson Worksheet: Specific Immune Response: Antibodies Biology
In this worksheet, we will practice describing the process of clonal expansion and antibody formation in response to an antigen.
What type of immune cell is activated by the presence of a processed antigen on the surface of B cells and macrophages?
- APlasma cell
- BB memory cell
- DT-helper cell
- ENatural killer cell
What cellular process is necessary before antigens can be processed and presented?
How are memory cells different from plasma cells?
- AMemory cells are no longer able to multiply and differentiate.
- BMemory cells have only one type of antibody receptor on their cell surface whereas plasma cells have many different types of antibody receptors.
- CMemory cells have a higher rate of protein synthesis.
- DMemory cells remain in the circulation for a longer time period.
- EMemory cells are able to respond to a wider range of antigens.
HIV infects and destroys T-helper cells. How would an HIV infection affect the body’s antibody response to a new bacterial infection?
- AThe antibody concentrations would rise higher and faster.
- BOnly one type of antibody would be produced.
- CThe same level of antibodies would be produced but it would take longer.
- DFewer antibodies would be produced by B cells.
- EThere would be no effect on the antibody response.
What triggers the activation of a B cell to start clonal expansion?
- ABinding to a specific antigen and interleukin release from a T-helper cell
- BBinding to a specific T-helper cell and interleukin release from a natural killer cell
- CBinding to a specific macrophage and interleukin release from a T-helper cell
- DBinding to a specific T-helper cell and interleukin release from a macrophage
- EBinding to a specific antigen and interleukin release from a macrophage
The figure shows a B lymphocyte with antibody (immunoglobulin) receptors on its surface membrane.
Which statement is not true?
- AEach B cell will have a different type of antibody receptor on its surface.
- BEach B cell has only one type of antibody receptor that binds to one specific antigen.
- CThe B cell antigen receptor has a similar structure to a soluble antibody.
- DThe B cell can bind to extracellular and intracellular antigens.
- EThe B cell antibody receptor is complementary to an antigen.
The figure shows a pathogen that has entered the body.
How many types of B cells and antibodies would be formed as a result of the stimulation of the humoral immune system?
- AFour B cell clones and four different types of antibodies
- BFour B cell clones and fifteen types of antibodies
- COne B cell clone and fifteen types of antibodies
- DOne B cell clone and four types of antibodies
The figure shows a type of cell surface protein (in green), called MHC, present on B cells.
What is its function?
- ATo respond to interleukins from T-helper cells
- BTo bind with another type of antigen on a pathogen
- CTo activate phagocytosis in neutrophils
- DTo present processed antigens for T-helper cells to detect
- ETo bind to the histamine released from mast cells