Worksheet: Combining 1D and 2D NMR Data

In this worksheet, we will practice determining structures using chemical shifts, splitting patterns, and correlation data in several 1D and 2D NMR spectra.


When a nucleus is irradiated in an NMR experiment, the induced change in magnetization can be transferred to another nucleus via through-space interactions. What name is given to the variant of NMR spectroscopy that utilizes this effect?

  • AHeteronuclear correlation spectroscopy (HETCOR)
  • BDistortionless enhancement by polarization transfer spectroscopy (DEPT)
  • CHeteronuclear single quantum correlation spectroscopy (HSQC)
  • DCorrelation spectroscopy (COSY)
  • ENuclear overhauser effect spectroscopy (NOESY)

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