Worksheet: Drug Development

In this worksheet, we will practice recalling the main steps in developing new medicines, and explaining the importance of each step.

Q1:

Which of the following outlines the stages of drug development in the correct order?

  • ASimulate response with computer models test on cells test on animals test on patients with the disease test on healthy volunteers
  • BSimulate response with computer models test on cells test on animals test on healthy volunteers test on patients with the disease
  • CSimulate response with computer models test on cells test on healthy volunteers test on animals test on patients with the disease
  • DSimulate response with computer models test on animals test on cells test on healthy volunteers test on patients with the disease
  • ESimulate response with computer models test on animals test on healthy volunteers test on cells test on patients with the disease

Q2:

In clinical trials, a placebo is often used. What is a placebo?

  • AA group of cells that can be tested to check the drug for toxicity
  • BA substance that contains a high concentration of the drug being tested
  • CA substance that does not contain the drug being tested
  • DA group of volunteers that do not have the disease

Q3:

What key term in drug development describes any unintended changes to the body that are caused by drugs?

  • ASide effects
  • BContamination
  • CInfections
  • DPlacebo

Q4:

Complete the following description of a double-blind trial:

A double-blind trial is when neither the nor the researchers know who has been given the drug and who has been given the .

  • Apatients, placebo
  • Bpharmacists, second drug
  • Cdoctors, drug substitution
  • Dvolunteers, diet pill

Q5:

In clinical trials, why is the drug tested on healthy volunteers before it is given to people suffering from the disease?

  • ATo see if the drug cures any other diseases
  • BTo determine the type of disease that can be treated by the drug
  • CTo see if the drug cures or treats the intended disease
  • DTo determine if there are any harmful side effects

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