Lesson Worksheet: Drug Development Biology
In this worksheet, we will practice recalling the main steps in developing new medicines and explain the importance of each step.
Q1:
What key term in drug development describes any unintended changes to the body that are caused by drugs?
- ASide effects
- BContamination
- CInfections
- DPlacebo
Q2:
Which of the following outlines the stages of drug development in the correct order?
- ASimulate response with computer models test on cells test on animals test on patients with the disease test on healthy volunteers
- BSimulate response with computer models test on cells test on animals test on healthy volunteers test on patients with the disease
- CSimulate response with computer models test on cells test on healthy volunteers test on animals test on patients with the disease
- DSimulate response with computer models test on animals test on cells test on healthy volunteers test on patients with the disease
- ESimulate response with computer models test on animals test on healthy volunteers test on cells test on patients with the disease
Q3:
In clinical trials, a placebo is often used. What is a placebo?
- AA group of cells that can be tested to check the drug for toxicity
- BA substance that contains a high concentration of the drug being tested
- CA substance that does not contain the drug being tested
- DA group of volunteers that do not have the disease
Q4:
In clinical trials, why is the drug tested on healthy volunteers before it is given to people suffering from the disease?
- ATo see if the drug cures any other diseases
- BTo determine the type of disease that can be treated by the drug
- CTo see if the drug cures or treats the intended disease
- DTo determine if there are any harmful side effects
Q5:
Complete the following description of a double-blind trial:
A double-blind trial is when neither the nor the researchers know who has been given the drug and who has been given the .
- Apatients, placebo
- Bpharmacists, second drug
- Cdoctors, drug substitution
- Dvolunteers, diet pill
Q6:
Which of the following is not a reason drugs are tested in preclinical trials before being used in humans?
- ATo ensure they can be produced on a mass scale
- BTo determine if there are any side effects
- CTo determine their efficacy (if they work)
- DTo ensure they are not toxic
- ETo determine a safe dosage to be used in clinical testing
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