Worksheet: Mutations

In this worksheet, we will practice describing mutations, and explaining the impacts mutations can have on organisms.

Q1:

A student said, “Mutations in noncoding DNA have no effect on gene expression.”

Is this true or false?

  • AFalse
  • BTrue

Q2:

A student said, “All mutations have harmful effects.”

Is this true or false?

  • ATrue
  • BFalse

Q3:

A student said, “Mutations occasionally cause cells to divide out of control, which can lead to cancer.”

Is this true or false?

  • ATrue
  • BFalse

Q4:

When is a gene said to be expressed?

  • AA gene is expressed when it becomes visible within the cell.
  • BA gene is expressed when the sugar it codes for is made in the cell.
  • CA gene is expressed when it is replicated within the cell.
  • DA gene is expressed when the protein it codes for is made in the cell.
  • EA gene is expressed when its DNA base sequence is irreversibly changed.

Q5:

The diagram given shows the changes in a section of DNA.

Which of the following best describes what has happened to the section of DNA?

  • ASome of the DNA bases have been deleted.
  • BSome DNA bases have switched places.
  • CSome DNA bases have been inserted into the sequence.
  • DThe order of the DNA bases has changed.
  • EThe DNA has decreased in size.

The new section of DNA undergoes transcription. Which of the following best describes the impact this could have?

  • AThe correct RNA will no longer be transcribed, so the correct mRNA will not be made.
  • BThe correct gene will no longer be transcribed, so the correct protein will not be made.
  • CThe correct gene will no longer be transcribed, so the correct DNA will not be made.
  • DThe correct gene will no longer be translated, so the correct phenotype will not be made.
  • EThe correct protein will no longer be transcribed, so the correct gene will not be made.

Q6:

A student said, “Mutations in coding DNA can change the shape of the protein made.”

Is this true or false?

  • ATrue
  • BFalse

Q7:

A mutation occurs in a noncoding section of DNA. This section of DNA regulates transcription of the gene OCA2. Which of the following best describes what could happen?

  • AThe OCA2 is not translated into DNA, so the protein it codes for cannot be made.
  • BThe OCA2 gene is not transcribed into DNA, so the protein it codes for cannot be made.
  • CThe OCA2 gene is not translated into mRNA, so the protein it codes for cannot be made.
  • DThe OCA2 gene is not replicated, so the protein it codes for cannot be made.
  • EThe OCA2 gene is not transcribed into mRNA, so the protein it codes for cannot be made.

Q8:

Most mutations that occur in organisms are neutral. What does this mean?

  • AThey benefit, but do not harm, the organism they occur in.
  • BThey harm the organism they occur in.
  • CThey are both harmful and beneficial to the organism they occur in.
  • DThey do not occur in coding sections of the DNA.
  • EThey do not harm or benefit the organism they occur in.

Q9:

What is a mutation?

  • AA break in the hydrogen bonds between base pairs
  • BA change in the DNA base sequence
  • CA dangerous addition to a cell or organism
  • DA change in the sugar–phosphate backbone

Q10:

Which of the following best describes a gene?

  • AA section of RNA that contains instructions for synthesizing a sugar
  • BA section of DNA that contains instructions for synthesizing a lipid
  • CMultiple sections of DNA that contain instructions for synthesizing a phenotype
  • DA section of DNA that contains instructions for synthesizing a protein

Q11:

A mutation occurs in a section of DNA that codes for an amino acid sequence found in an enzyme’s active site. Which of the following best describes what could happen?

  • AThe protein will react differently and the enzyme will be killed.
  • BThe enzyme’s active site will have to be repaired by fixing enzymes.
  • CThe DNA will be transcribed into tRNA rather than mRNA.
  • DThe protein will fold differently and the active site will change shape.

Nagwa uses cookies to ensure you get the best experience on our website. Learn more about our Privacy Policy.