Worksheet: COSY NMR Spectra

In this worksheet, we will practice using 2D correlation spectra to determine which protons in a compound show significant spin–spin coupling.

Q1:

In a COSY spectrum, the dark spots along the diagonal .

  • Ado not give any structural identification because they are too intense to be deconvoluted
  • Ballow distinctions to be made between heteronuclear coupling constants
  • Cgive the most structural information because they differentiate between different hybridizations
  • Ddo not yield structural information because they correspond to the same peak on each coordinate axis

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