Worksheet: Human Defences Against Disease

In this worksheet, we will practice describing the physical and chemical defences of the human body.


Fill in the blanks: Pathogens are prevented from infecting our eyes by ; these contain , which break(s) down bacteria.

  • Amucus, enzymes
  • Btears, lysozyme
  • Ctears, sulfuric acid
  • Dhairs, mucus
  • Ecilia, enzymes


Which of the following describes how the stomach prevents pathogens from infecting humans?

  • AThe stomach produces antibiotics to break down and destroy any bacterial pathogens.
  • BThe stomach compresses after eating to squash and kill any pathogens.
  • CThe stomach contains acid that kills pathogens that have contaminated any food or drink a person consumes.
  • DThe stomach is lined with cilia that traps pathogens and moves them down the digestive system.
  • EThe stomach is lined with hairs that produce enzymes to break down pathogens.


Which of the following is an example of a physical defense against disease in humans?

  • AAntifungals
  • BHydrochloric acid in the stomach
  • CThe skin
  • DLysozyme in tears
  • EAntitoxins


Which of the following is an example of a chemical defense against disease in humans?

  • AHydrochloric acid in the stomach
  • BThe skin
  • CA waxy cuticle
  • DCilia in the airways
  • ECell walls


Which structure prevents pathogens from entering the human respiratory system by trapping dust and microorganisms in mucus?

  • AEyes
  • BAlveoli
  • CNasal hairs
  • DBronchioles
  • EThe stomach


Which of the following terms best describes defenses like skin, nasal hairs, and stomach acid?

  • ANonspecific
  • BSpecific


Is the presence of lysozyme in tears a chemical or a physical defense?

  • APhysical
  • BChemical

Are nasal hairs a chemical or a physical defense?

  • AChemical
  • BPhysical

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