Question Video: Identifying the Type of Bonds that Form Between DNA Base Pairs Biology

What type of bond forms between base pairs in DNA to hold the two strands together in a double helix? [A] Glycosidic [B] Hydrogen [C] Ionic [D] Covalent [E] Phosphodiester

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Video Transcript

What type of bond forms between base pairs in DNA to hold the two strands together in a double helix? (A) Glycosidic, (B) hydrogen, (C) ionic, (D) covalent, or (E) phosphodiester.

This diagram represents the double-helix structure of DNA. If we zoom in on a small section of this DNA molecule, we can see that it’s made of individual units that we call nucleotides. Each nucleotide contains a base. There are four different possible bases, as represented by the four different colors you see here. A special type of covalent bond called a phosphodiester bond forms between nucleotides. These phosphodiester bonds form the two strands that make up the DNA molecule. But this question is asking us what bonds form between base pairs to hold the two strands together. So we can rule out (E) because phosphodiester is not the correct answer.

The bonds that form between base pairs are hydrogen bonds. As you can see on this diagram, two hydrogen bonds form between thymine and adenine, which are the names of these two bases, and three hydrogen bonds form between guanine and cytosine, which are the names of the other two bases. We have therefore determined that the type of bond that forms between base pairs in DNA to hold the two strands together in a double helix is (B) hydrogen.

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