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Question Video: Recalling the Bond Peptidyl Transferase Catalyzes Biology

Peptidyl transferase catalyzes the _ bond formation to link two amino acids in a growing polypeptide chain. [A] hydrogen [B] ester [C] glycosidic [D] peptide

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Video Transcript

Peptidyl transferase catalyzes the blank bond formation to link two amino acids in a growing polypeptide chain. (A) Hydrogen, (B) ester, (C) glycosidic, (D) peptide.

In order for a gene in DNA to be converted into a protein, it needs to go through two steps. The first step is called transcription and involves converting DNA into mRNA. The second step is called translation, where the sequence of mRNA is converted into a sequence of amino acids to form a polypeptide. This polypeptide can then go on to fold into a protein with a specific shape and function. Let’s talk about some of the details of translation to answer this question.

Translation is performed by an organelle called the ribosome. It is made up of two subunits, the large and small subunit that sandwich together the mRNA molecule. The sequence in mRNA is matched to incoming tRNA molecules that bring the corresponding amino acid. These amino acids are linked to the growing polypeptide chain that is coded for by the mRNA sequence. The ribosome links these incoming amino acids using its peptidyl transferase enzymatic activity. This new bond that peptidyl transferase forms is called a peptide bond.

Therefore, in the statement “Peptidyl transferase catalyzes the blank bond formation to link two amino acids in a growing polypeptide chain,” the answer choice that correctly fills in the blank is given by answer choice (D), peptide.

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