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Question Video: Identifying the Factors Involved in Blood Clotting Biology

The flow chart outlines the basic process of how a blood clot forms at the site of a wound. What word would correctly replace the gap in statement 2?

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Video Transcript

The flow chart outlines the basic process of how a blood clot forms at the site of a wound. What word would correctly replace the gap in statement two? (A) Collagen, (B) fibrinogen, (C) hemoglobin, or (D) thromboplastin.

When a blood vessel is damaged, platelets are attracted to the injury site. When they adhere to this site of damage, it causes them to activate. This attracts more platelets to the site of the injury, which together form a temporary platelet plug. When this plug forms, a series of biochemical reactions to form a clot is triggered. This is what the flowchart depicts.

The first in this sequence of reactions is that the damaged cells release thromboplastin, which is a tissue factor that, with the help of calcium ions, converts the blood component protein prothrombin into the enzyme thrombin. Thrombin is an enzyme that catalyzes the conversion of the blood component fibrinogen into fibrin threads, which form a fibrous net over the injured area.

So, in the sequence of the flowchart, first a blood vessel is damaged. Then damaged blood vessels release the tissue factor thromboplastin. After that, if calcium ions are present, thromboplastin initiates the conversion of prothrombin to thrombin. And then thrombin, an active enzyme, catalyzes the conversion of fibrinogen into fibrin so that finally fibrin forms a net to trap red blood cells. And the blood cells and fibrin aggregate to form a clot.

So the word that correctly replaces the gap in statement two is (D). Damaged blood vessels release the tissue factor thromboplastin.

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