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Lesson Plan: Specific Immune Response: Antibodies Biology

This lesson plan includes the objectives, prerequisites, and exclusions of the lesson teaching students how to describe the process of clonal expansion and antibody formation in response to an antigen.


Students will be able to

  • describe how antigens on pathogens trigger the production of antibodies (humoral immunity),
  • describe the process of clonal expansion in antibody production,
  • recall that plasma cell antibodies cannot destroy cells infected by viruses.


Students should already be familiar with

  • the structure of an antibody,
  • the specificity of antigen–antibody binding,
  • how antibodies facilitate the removal of a non-self-antigen,
  • T and B lymphocytes,
  • mitosis and differentiation as concepts.


Students will not cover

  • cell-mediated immune response,
  • primary and secondary immune responses.

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